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Investigating the mechanisms by which oxidative stress affects epigenetic modifications in sperm and how these modifications may influence embryonic development and offspring health is a promising area of research that could have significant implications for reproductive medicine

High Doses of Nicotinamide Prevent Oxidative Mitochondrial Dysfunction in a Cellular Model and Improve Motor Deficit in a Drosophila Model of Parkinsons Disease

We highlight cell-typespecific roles of Nrf2 in neurons, astrocytes, and microglia, and the gene expression networks that drive CNS antioxidant and detoxification responses

10.1007/s12311-016-0763-3 35 CallaghanR

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