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Indeed, DCI was first described as an insulin second messenger and detected only in insulin-responsive tissues [34]

Tamalunas A, Sauckel C, Ciotkowska A, Rutz B, Wang R, Huang R, et al

Increased glycolytic ATP synthesis is associated with tafenoquine resistance in Leishmania major

Because H 2 S and Fe 2+ are abundant in hydrothermal environments, primitive organisms likely extracted two electrons of reducing power from oxidation of H 2 S, which then coupled with Fe 2+ , yielding pyrite (FeS 2 )[20]

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