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According to the report of the World Health Organization (WHO), 11 parasitic diseases have been listed as Neglected Tropical Diseases (NTD) that infect over 1 billion people worldwide ( Generally, the prevention and control strategies for parasitic diseases mainly rely on eliminating infection sources, blocking transmission routes, and protecting susceptible populations

Larjava, H., Plow, E

However, some studies have utilised between 8 and 24 h to represent the colon [68, 69], because there is a large intra-individual variation in small intestinal transit time (from 50460 min) [70]

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This effect was accompanied by downregulation of RAF and RAS mRNA and protein expression, suggesting a potential combinatorial therapeutic strategy ( Effects of curcumin on endometrial cancer The development of EC is driven by a complex interplay of risk factors, including obesity, diabetes, family history, hormonal imbalances, PCOS, hormone therapy, use of intrauterine devices, and endometrial hyperplasia ( Curcumin also targets anti-apoptotic molecules such as TREK-1 to reduce cell proliferation in EC cells ( in vivo models, including NOD-SCID mice, daily intraperitoneal curcumin injections (50 mg/kg) for 30 days led to a fivefold reduction in tumor volume without observed toxicity ( Curcumin also interferes with AR signaling, which plays a role in EC pathophysiology

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