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Doctors prescribe it for specific medical indications, for example, children with poor growth due to low GH, or adults with confirmed GH deficiency causing symptoms

Cases of allergic reactions to hydroxocobalamin with tolerance to cyanocobalamin were documented in several instances (1, 2, 3)

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Other outbreaks have been linked to aerosol (mist) sources in the community or with cruise ships and hotels, with the most likely sources being hot tubs, cooling towers (air-conditioning units from large buildings), and water used for drinking and showering. To prevent the build up of the Legionella bacteria, Occupational Safety & Health Administration (OSHA) recommends that water systems be properly inspected and maintained with frequent flushing of domestic water systems at very high temperatures

JAMA 327 , 12361246 (2022)