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Certain medications particularly insulin secretagogues or other glucose-lowering agents may need dose adjustments when combined with semaglutide due to its glycemic effects

66th Scientific Sessions Abs 485-P (2006)

Dosing Protocol The parallel escalation used in the REDEFINE trials, converted to U-100 units at 10 mg/mL total (5 mg/mL of each component)

As I said before PA is still thought to be the primary culprit here, other causes of B12 deficiency such as malabsorption caused by metformin, H2 blockers, PPIs, parasites, etc