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Zhu J, Cui Y, Zhang J, et al

& Warshaw, R

Obstructive sleep apnea and insight into mechanisms of sympathetic overactivity

This FOXO4-p53 interaction occurs within nuclear PML (promyelocytic leukemia) bodies and is critical for maintaining the viability of senescent cells without it, p53 is free to translocate to mitochondria and trigger intrinsic apoptosis