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Pictorial warnings are not as graphic or overt as they are for cigarettes, leading some people to believe smoking bidis is actually the safer alternative

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People with serious mental illness and substance use disorders smoke at far higher rates than the general population and die disproportionately of tobacco-related disease addressing nicotine during SUD treatment is increasingly standard of care rather than an afterthought

Withdrawal is characterized by negative affective states (irritability, anxiety, depression, anhedonia) and craving, partly mediated by dopamine deficits and activation of stress pathways involving corticotropin releasing factor

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