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2014;8(12) doi: 10.1371/journal.pntd.0003278

The first total synthesis of ()-mitragynine, an analgesic indole alkaloid in Mitragyna speciosa

There are two principles

discovered that MWCNT instillation reduced the mRNA expression of CPT1, CPT2, and PPAR coactivator 1 alpha in permeabilized bronchoalveolar lavage cells, accompanied by elevated oxidative stress in alveolar macrophages and inflammatory injury of murine lung tissues (Huizar et al., 2013)