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In addition, hemodynamic alterations, such as increased cardiac pre- and afterload, contribute to mechano-energetic uncoupling in HF, especially with preserved ejection fraction (HFpEF), which results in mitochondrial oxidative stress as an important upstream mediator of cardiac remodeling and dysfunction [2]

B Complex Assists with stress reduction and digestion

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doi: 10.1017/s1092852924000518 34 KhavariBMahmoudiEGeaghanMPCairnsMJ

COVID-19, coronavirus disease 19

Images were collected using a CFI Plan Apochromat Lambda D oil immersion objective (60, NA = 1.4) and for roGFP imaging a CFI Plan Apo VC water immersion objective (60, NA = 1.2)