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Furthermore, the transcription factor NFE2 like bZIP transcription factor 2 (NFE2L2, best known as NRF2) is a pivotal regulator of the antioxidant system and controls the expression of genes central to antioxidant defense mechanisms [28]

Rheumatol Int (2013) 33:18837

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In environmental contexts, even low levels of AgNPs reduced metabolic diversity in organic-matter-associated microbial communities, which in turn indirectly stunted invertebrate growth in aquatic food webs (Zhai et al., 2018

Given its long history of consumption as part of citrus fruits, the safety of auraptene has been well-established over millennia (Vakili et al., 2017)