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Dhanya CR, Gayathri NS, Mithra K, Nair KV, Kurup PA

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Peptide cleavage and purification Dried peptide-containing resin was suspended in 1.5 ml cleavage cocktail (2.5% DODT, 2.5% H 2 O, 2.5% TIPS in TFA) per 100 mg resin and agitated for 2 h

5-Amino-1MQ (5-amino-1-methylquinolinium) is the most studied inhibitor of nicotinamide N-methyltransferase (NNMT) an enzyme that acts as a metabolic brake in fat cells by depleting both SAM (S-adenosylmethionine) and NAD+ precursors

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