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In its active state, it binds and activates its effector proteins such as RAF-Kinases, PI3K and RalGDS and activates several cellular signaling pathways including mitogen-activated protein kinase (MAPK) pathway

The emerging role of lysosomes in copper homeostasis

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Luminescence was read by a victor3 1420 multilabel counter (Perkin Elmer)

6) as opposed to the reduction of the glutathionylated monothiol roGFP2 variants (Fig