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The primary objective of this study is to examine the adverse impacts of busulfan on various rat organs, such as the liver, kidneys, testes, and bone marrow, utilizing histological, biochemical, and cytological assessments [41, 89]

Concurrently, cisplatin induced severe glutathione depletion (Figure 3B), MDA elevation (Figure 3C), and ROS overproduction (Figures 3D,E)

PMID: 32247225

Neonatal screening for biotinidase deficiency: results of a 1-year pilot study

This classification was received because the Cognilum device does not fulfill the criteria for a significant risk (SR) device as defined under 21 CFR 812.3(m) of the investigational device exemptions (IDE) regulation (21 CFR 812)

The biological instability of nanoparticles could also be attributed to enzymatic degradation that compromises the structural integrity of nanoparticles (Guerrini et al., 2018)