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9 Can too much selenium be harmful

Other conditions in which overproduction of oxidants is experienced include but are not limited to amyotrophic lateral sclerosis, atheroscierotic cardiovascular disease and multiple organ dysfunction

doi: 10.1073/pnas.2213120119 112

However, the systemic immune-related adverse events (irAEs) associated with PD-1/PD-L1 antibodies can be life threatening, due to their long half-lives