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Different groups of patients and candidates for IGF-1 treatment have been those with an IGF-1 gene deletion and others with idiopathic short stature

Three FDA approvals and multiple international approvals confirm its clinical utility

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What the human evidence looks like How many human studies exist The 2025 systematic review by Vasireddi, Hahamyan, Salata, and colleagues in HSS Journal is the most rigorous available assessment of the BPC-157 literature (19932024) for orthopedic and sports medicine applications