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5) Sleep Disturbances Sleep disruption has been reported, including: Difficulty falling asleep Fragmented sleep Restlessness As NNMT inhibition may influence neurotransmitter regulation and methylation-dependent processes, circadian rhythm alterations are theoretically possible

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doi:10.1056/NEJMoa2307563 Jastreboff AM, Kaplan LM, Frias JP, et al

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