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Arisoy et al

However, KYNA influences AMPAR activity predominantly through indirect mechanisms, namely its non-competitive allosteric inhibition of presynaptic 7nAChRs on glutamatergic terminals in mood-related circuits, leading to reduced glutamate release and downstream modulation of excitatory signalling [29, 30]

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Cells were harvested 48 h after transfection either in growth medium or after 24 h in starvation medium

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