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For example, gut microbiota metabolites such as short-chain fatty acids (SCFAs) and tryptophan derivatives indirectly affect ferroptosis by regulating oxidative stress and iron metabolism

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OPZ concentrations were 0 (), 25 (), 50 (), 75 (), and 100 () M

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Taken together, the versatile capabilities of mitochondria in bioenergetics and biosynthesis could trigger lipid peroxidation to ferroptosis

Int J Dev Neurosci 25:391398 Schuck PF, Milanez AP, Felisberto F, Galant LS, Machado JL, Furlanetto CB, Petronilho F, Dal-Pizzol F, Streck EL, Ferreira GC (2015) Brain and muscle redox imbalance elicited by acute ethylmalonic acid administration