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It is noteworthy that due to their unique structural properties, polyphenols form multiple interactions with peptides and polysaccharides and chelate with metal ions to form a secondary network

However, compound 34 with a 5-chloro-2-fluoro substituted phenyl ring displayed the highest EC 50 in the RNA reduction-based assay and had considerably higher EC 50 in the CPE-based assay compared to other halide-substituted ebselen diselenide derivatives ( 25 , 27 , 30 )

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There is research suggesting that methylcobalamin may be particularly supportive in neurological conditions compared to cyanocobalamin, likely because of its direct involvement in methylation and nerve tissue repair

Besides this, there is an increase in the generation of NADPH and GSH, an antioxidant, and redox cofactors such as NADH and FADH