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Keap1 mutation renders lung adenocarcinomas dependent on Slc33a1

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Several animal studies have demonstrated that BCAAs, particularly leucine, exert significant effects on skeletal muscle protein such as stimulation of muscle protein synthesis also by possible interactions with the innate immune system with resulting modified cytokine expression [33]

Verma RJ

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For instance, glutamine increased the production of T H 1 cytokines IL-2 and IFNy by activated murine IELs and by human lymphocytes and PBMCs, while T H 2 cytokines were unaltered (168171)