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Poor diet, stress, chronic illness, and aging can all contribute to a lack of essential nutrients

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Consequently, BMP-2 mimetic peptides have been developed as potential substitutes for bone regeneration due to their advantages including low cost and feasibility for large-scale synthesis

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For those with irreversible causes such as pernicious anaemia or malabsorption, injections are usually given every 23 months

Oral supplementation is a standard treatment for B12 deficiency