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Without such concerted efforts, the enormous therapeutic promise of ferroptosis modulation may remain confined to the preclinical realm

Typically, high doses (i.e., 5-10 grams) of glutathione are required to increase glutathione levels

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Optimization studies confirmed that ultrasonic irradiation in ethanol offered the best performance, whereas non-polar and aprotic polar solvents were less effective, and polar protic solvents such as isopropanol and methanol led to longer reaction times and lower yields compared to ethanol

Oil-based lube is listed as "not recommended" rather than "not safe" for most materials because the issue isn't chemical damage - it's that oil is difficult to clean from toys and can create an environment for bacterial growth

Li CH, Ou JH, Chen CY