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510 Triacsin C can improve PD by inhibiting of ACSL4 activity, 602 and clausenamide also improves behavioral deficits in PD mouse models by blocking nuclear translocation of ALOX5

Caspase-3 is known to be activated by ROS [54, 78] and promote PS externalization in eryptosis [135, 136]

In a similar way, acrolein appears to stimulate oxidative stress damage, producing high levels of ceramide, which is accountable for the incrementation of cytosolic Ca 2+ concentration and, consequently, the eryptosis levels [254]