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Ascorbate and glutathione can individually participate in ROS detoxification operations, but their essential role results from their association in the context of the ascorbate-glutathione cycle (AGC), also called the Halliwell-Asada-Foyer cycle, after the scientists who identified it (see Focus on Hydroperoxide detoxification)

Other copper metabolism disorders similarly contraindicate GHK-Cu use

[DOI] [PubMed] [Google Scholar] 248.Shelton MD

This imbalance can lead to cellular damage and has been associated with various pregnancy complications, including preeclampsia and gestational diabetes

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