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The mechanism was proposed to involve copper-dependent enzymes (notably lysyl oxidase, which catalyzes the cross-linking of collagen and elastin and requires copper as a cofactor), GHK-specific effects on growth factor activity, and downstream gene-expression effects in fibroblasts and other tissue-repair-relevant cell types

Abstract Background Oleaginous microorganisms contain oil and fat at amounts greater than 20% of their biomass weight, with fatty acid and chemical compositions often similar to those of vegetable oil and animal fat

The synergistic effect of inflammatory molecules and leukocyte infiltration disrupts the BBB and promotes leakage of serum proteins (68, 143)

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Harrison FE, Bowman GL, Polidori MC

A complete list of differential gene scores for each screen is provided in Extended Data Table 2