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E2 supplementation restores membrane lipid integrity by enhancing expression of antioxidant enzymes and reducing oxidative phospholipid generation, thereby limiting inflammatory phospholipid signalling and complement activation

Initial screening primarily focuses on abnormalities in copper metabolism, including serum ceruloplasmin levels and baseline 24-hour urinary copper excretion

Djafari, J

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de Groot, S

The cAMP-mediated PKA/extracellular signal-regulated kinase (ERK) pathway also contributes to the regulation of antioxidant enzymes, which in turn aids in the prevention of skin aging