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Description

The drug amplifies the caloric deficit created by healthy eating and exercise

the main pathways differing between the FI group and the GSH group were Gap junction, Aminoacyl-tRNA biosynthesis, Pyrimidine Metabolism, D-Amino acid metabolism

[PubMed: 17512232] 226

Manthey J, Solovei A, Anderson P, Carr S, Rehm J

Its design illustrates a radical peptidomimetic : only two amino acid residues (Tyr-Ile) are preserved from the native peptide, flanked by non-peptide acyl chains to cross biological barriers