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10.3171/jns.1996.84.2.0229 J

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The significant correlation between Kla-specific genes and lactate accumulation-related genes (e.g., P300, LDHA) reveals that Kla promotes BC progression and immune escape by affecting NK cell function and multiple signaling pathways (NOTCH, WNT, among others) (117)

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Apoptosis related spot like protein knockout (ASC -/- ) and IL-1R1 -/- mice demonstrated reduced lung inflammation and increased survival rates following H7N9 infection