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The compartmentation of cAMP signaling in the heart arises, in part, from specific signaling complexes which generate distinct cell responses, with AC5 and AC6 being central effectors to the formation and maintenance of these compartments

They were Group 1: the control group (without treatment), group 2: the sham group, normal saline (solvent of the MSG and L-carnitine), group 3: the healthy group (L-Ca 200) (received the L-carnitine 200 mg/kg b.w), group 4: MSG 3 g/kg b

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The count data were filtered to remove genes with low expression, transformed using the variance stabilizing transformation from the DESeq2 package (51), and then batch corrected using ComBat (52)