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Effects of short-term, medium-term and long-term resistance exercise training on cardiometabolic health outcomes in adults: systematic review with meta-analysis

It is characterized by persistent synovitis, progressive degradation of articular cartilage, secondary formation of osteophytes, and remodeling of subchondral bone ( The main pathological characteristics of OA include the loss of chondrocytes, degradation of the cartilage matrix, and synovitis, ultimately leading to terminal OA ( The endogenous indole hormone melatonin is primarily secreted in the pineal gland, synthesized from tryptophan through a series of derivative reactions ( 2 The role of oxidative stress, inflammation, and chondrocyte death in OA 2.1 Oxidative stress in OA The imbalance between oxidation and antioxidants leads to oxidative stress ( 2 - ), hydroxyl radical (OH-), hydrogen peroxide and (H 2 O 2 )

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4-methyl delta-lactone, marbolactone, delta-decalactone, potato lactone), methyl sorbate, penicillin, 4-hydroxy-2 (or 5) -ethyl-5 (or 2) -methyl-3 (2H) furanone, 2-hydroxy-3-methyl-2-cyclopentenone, 3-hydroxy-4, 5-dimethyl-2 (5H) -furanone, fruit esters and fruit lactones (e.g

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