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Along with autoxidation (50), another important oxidative pathway is the reaction between H 2 O 2 and both ferrous and ferric Hb, resulting in heme degradation and release of free iron (3), as described in detail before (150)

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368,369 Enhancing autophagy can mitigate nerve damage in DPN

In a human clinical trial, a marked increase in cellular glutathione levels was seen regardless of its initial (basal) concentration

Cerebellar atrophy is a universal feature of A-T but is non-specific