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The methaemoglobinaemia induced in these mice by sodium nitrite peaked later and at a lower level than the methaemoglobinaemia induced by hydroxylamine or 4-dimethylaminophenol, but was longer lasting (Kruszyna et al., 1982)

Most of the risks of these compounds stem from the absence of clinical trials and reliable data in humans, making it impossible to establish appropriate dosing, long-term safety, or adverse event profiles

It may have nothing to do with the B12 itself

Critical Care / Intensive Care Units (ICU)

Walker 2020 AOD-9604 Dosage Protocol: Subcutaneous Injection Timing For subcutaneous research use, 250500 mcg once daily is the standard starting range

Contraindications You should not receive MIC+B12 injections if you: Have a known allergy or hypersensitivity to any of the ingredients (e.g., methionine, inositol, choline, vitamin B12) or their preservatives