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Regression analyses were based on all time points, except for samples incubated with aspartate + -ketoglutarate and oxaloacetate + glutamate

For the modelling of second-order fluorescent data, EEM representing each sample was unfolded into a vector of 2444 features (see the Data analysis section), and then, these unfolded vectors were arranged into a data matrix of 56 2444

1 h before test Result:Increased the threshold of clonic seizures and tonic phase of seizures with lethal outcome in a dose of 500 mg/kg

97% of the given patients showed significant resolution of clinical symptoms and signs associated with opiate withdrawal after 2 weeks