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Intriguingly, BRCA1/BRCA2-containing complex subunit 36 (BRCC36), a member of the JAMM family, has been suggested to regulate the switch between ferroptosis and pyroptosis

The carriers of CYP3A5 rs776746 A allele were overrepresented in the intentionally overdosed group and were more predisposed to acetaminophen-induced hepatotoxicity than individuals with the G allele, that rendered CYP3A5 enzyme inactive due to aberrant gene splicing [100]

Tonnus et al

Immunol Res 30:261277 Duprez DA, Neuhaus J, Kuller LH et al (2012) Inflammation, coagulation and cardiovascular disease in HIV-infected individuals

Weyand CM, Wu B, Huang T, Hu Z, Goronzy JJ