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Everything below is either preclinical animal work, a theoretical concern drawn from the proposed mechanism, or self-reported community anecdote each labeled by source class so the evidence weight is never blurred

-Synuclein is degraded by both autophagy and the proteasome

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I get a lot of pushback on that from physicians saying, Why would you want to burden a patient with that knowledge? I welcome that debate because it opens a discussion: Do you or do you not believe that this a deterministic gene

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