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Moreover, although the autophagy of mitochondria (mitophagy) may sequester iron in mitophagosomes to prevent iron from releasing into the cytoplasm in the early stages of iron overload, extensive mitophagy can conversely trigger Fe 2+ liberation, elevate cytosolic Fe 2+ levels, and amplify ferroptosis (Yu et al., 2022

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The 90-degree angle (straight in) is appropriate when adequate tissue depth is present and no pinch is needed

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It is supplied strictly as a research compound for laboratory use and is not for human consumption