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Cell 173 , 291304 e6 (2018)

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The precise regulation of ALS pathogenetic mechanisms is still elusive, despite the abundance of identified mechanisms mediating MN degeneration and death, including neuroinflammation, glutamate excitotoxicity, altered RNA metabolism, mitochondrial dysfunction, impaired cytoskeletal integrity, altered axonal transport dynamics, OS [71, 84, 85]

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Thus we speculated that CSD suppresses inflammation in psoriasis by regulating STAT3 activation