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Journal of internal medicine

Where the evidence was convincing, we changed what we do

Given the importance of the cofactor in energy metabolism, NAD + is especially important in mitochondrial function, and in fact both NAD + and mitochondria are concentrated in energetically demanding tissues 1012

Neurological problems : Some people with coeliac disease may experience neurological symptoms, such as peripheral neuropathy, ataxia (impaired coordination), and epilepsy

Using the clinical trial escalation protocol (2mg starting dose with 2mg increases every 4 weeks), reaching the 12mg maintenance dose takes approximately 20 weeks

Pregnancy and Lactation: This medication is generally not recommended during pregnancy and breastfeeding unless specifically directed by your healthcare provider