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10.1098/rsob.180138 Open Biol

An imbalanced gut (dysbiosis) and a leaky gut lining can lead to chronic, low-grade systemic inflammation

Beyond the toxic gain-of-function effects of mHTT, HD pathogenesis involves a range of interconnected mechanisms, including mitochondrial dysfunction, transcriptional dysregulation, impaired autophagy, proteostasis failure, excitotoxicity, oxidative stress, and chronic neuroinflammation [3843]

Fortunately, there are several easy ways to increase your glutathione intake and maximize the rate at which it moves through your body

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We therefore needed include a blood compartment and to keep track of bCys, bGly, bGSH, bGSSG and bGlut