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It's a question that comes up a lot, and the short answer is that high B12 levels by themselves don't typically cause symptoms

We were exploring ways of developing peptides that bind selectively, and we were very successful at that, but then we confronted the problem that our short, 23-residue peptides are not promising therapeutic candidates primarily because they cannot get into cells, Keating says

Tucson has more of the desert to offer its visitors and residents but fewer jobs to offer newcomers