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Tissue samples from lean and ob/ob mice were homogenized in TRIzol reagent, followed by RNA extraction using standard protocols

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Theyre often used for anemia, and when both nutrients are low

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The mechanistic literature leans against a classic tolerance effect, not toward it

4) Blood Disorders Certain conditions affecting blood and bone marrow including some leukaemias and myeloproliferative disorders such as polycythaemia vera can cause elevated B12 due to increased production of B12binding proteins by white blood cells