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Description

In addition to being part of the TCA cycle, -KG is required for the function of -KG-dependent dioxygenases, including chromatin-modifying enzymes like histone demethylases, TET family of enzymes that are involved in DNA demethylation, and PHD enzymes

However, patients have been able to modify or manage symptoms through diet, nutrition, exercise, and stress reduction

Our flexible toolset is designed for people with homocystinuria to use with their caregivers and care teams to support the transition from childhood to adulthood