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10.1002/syn.10290 Synapse 371 YokotaE.KoyanagiY.YamamotoK.OiY.KoshikawaN.KobayashiM

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In all three AMYRs, P37 Cagri and Y37 rAmy occupy the same pocket above W79 ECD of the CTR ECD where they form conserved interactions with surrounding residues (Fig

Tirzepatide activates both GLP-1 and GIP receptors at once, so it engages a second hormone pathway that semaglutide does not