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The disease itself can lead to bone loss

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(9) Comorbidities of obesity and diabetes may also increase predisposition for falls, including peripheral neuropathy, obstructive sleep apnea, osteoarthritis, and femoral avascular necrosis

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By carefully considering these factors and tailoring the dosage to specific research objectives, investigators can optimize their use of SLU-PP-332 in metabolic studies and energy modulation research, leading to more meaningful and translatable results

In topical application, studies use concentrations of 0.01-1% in cream or serum formulations (Pickart et al., BioMed Res Int 2015For subcutaneous injection (research), doses vary depending on the experimental model