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These transcriptomic findings demonstrate that Retatrutide facilitates the remodeling of dysfunctional adipose tissue by coordinately inhibiting pro-fibrotic and adhesion signals while reinstating pro-homeostatic gene programs, thereby counteracting the fibrotic effects of a high-fat diet

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Yuanyi Peng, [email protected] Specialty section: This article was submitted to Nutritional Immunology, a section of the journal Frontiers in Immunology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers