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Now this, this theory of the HLA origin of innate immune activation has been contested by a number of practitioners whove sort of broken away from shoemakers original research
Abbreviations ALD: Alcoholic liver disease ANO1: Anoctamin-1 APAP: Acetaminophen ASCs: Adult stem cells CFTR: Cystic fibrosis transmembrane regulator COVID-19: Corona virus disease 2019 DILI: Drug-induced liver injury ESCs: Embryonic stem cells FFA: Free fatty acids GSH: Glutathione HBV: Hepatitis B virus HCV: Hepatitis C virus HEV: Hepatitis E virus HSCHep/HSC: HepaRG cells and hepatic stellate cells iPSC: Induced pluripotent stem cell IRI: Ischemia-reperfusion injury LDL: Low density lipoprotein LT: Liver transplantation NAFLD: Non-alcoholic fatty liver disease NASH: Non-alcoholic steatohepatitis PHHs: Primary human hepatocytes ROS: Reactive oxygen species SARS-CoV-2: Severe acute respiratory syndrome coronavirus 2 SHs: Small hepatocytes TNF: Tumor necrosis factor 2D: 2-Dimensional 3D: 3-dimensional References Asrani, S
Toxicol ., 35 (5), 447451
