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These possible complications include the following: Birth defects, miscarriage, or premature birth if taken during pregnancy Joint or bone pain, abnormal bone growth, and osteoporosis (bone thinning or weakening) Visual issues, including reduced night vision Hearing impairment Rare buildup of pressure inside the head (pseudotumor cerebri), with symptoms like blurred vision and nausea Mental health challenges like mood swings, depression, anxiety, or suicidal thoughts

In contrast, under alkaline conditions, the B-ring hydroxyl group of PCs becomes vulnerable to oxidation, resulting in a decrease in their antioxidant activity (40)

The most common side effects are associated with excessive adrenergic activation, including tremors, restlessness, transient rise in blood pressure, and mild palpitations

Acting through the ghrelin receptor, it promotes the release of GH and IGF-1, two key hormones linked to tissue growth, metabolic efficiency, and regeneration

Gastrointestinal disorder biomarkers

Upregulation of oxidative stress related genes in a chronic kidney disease attributed to specific geographical locations of Sri Lanka