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Moreover, the impact of chronic ethanol consumption on neurotrophic factors, particularly BDNF, is significant in the context of apoptosis and depression

For sample size, statistical methods were used (see figure legends)

In tier 2, a non-invasive screening strategy is applied to distinguish PDAC-associated diabetes from T2D by evaluating emerging blood biomarkers such as increased miRNAs, galectin-3, S100A9, adiponectin and IL-1Ra, glucagon/insulin ratio, vanin-1 and MPP9, cysteamine, lower GSH, lower PPAR-, and lower pancreatic polypeptide paired with an appropriate modeling strategy using the available clinical parameters for risk-assessment such as the Boursi multivariable model, ENDPAC, or machine-learning approaches such as XGBoost, to refine risk assessment (102108)

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Natural underlying mtdna heteroplasmy as a potential source of intra-person hipsc variability

Engineered human cardiac models of FRDA have also been reported [11]