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Kivisild, T

We further evaluate multiple therapeutic strategies targeting ferroptosis, including iron chelators, antioxidants, GPX4 activators, and lipoxygenase inhibitors

Conversely, short-term IP delivery provoked an acute cellular stress response

Additionally, by improving gut health, it can have a positive downstream effect on systemic inflammation

Critically, UGT inhibition (not substrate activity) correlates with hepatotoxic potential.A drugs inhibition of UGT enzymes is a direct indicator of increased hepatotoxicity risk

The authors are grateful to Vellore Institute of Technology (VIT, Vellore) for their support through the seed grant (RGEMS SG20250066)