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15,226,227 Recent therapeutic approaches focus on aldose reductase inhibitors (ARIs), such as epalrestat and ranirestat, which have shown promise in reducing sorbitol accumulation and ameliorating neuropathic symptoms in clinical trials

And while all forms of B12 are generally well-tolerated, clinically, doctors may find cobamamide to be the most well-tolerated of the three bioactive forms

Many patients notice improved energy, mental clarity, and hydration within hours of their infusion

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Taste: Many sublingual B12 supplements are flavored to improve the taste